NVP-ADW742

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Cat. No.: IBDI-434481

NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	IGF-1R \| Insulin Receptor \| Apoptosis
Molecular Weight	453.58
Appearance	Solid
Synonyms	ADW742, GSK 552602A, ADW
SMILES	NC1=C2C(N(C=C2C3=CC=CC(OCC4=CC=CC=C4)=C3)[[email protected]]5C[[email protected]@H](C5)CN6CCCC6)=NC=N1
Purity	99.54%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.