NW 1028

Cat. No.: IBDI-435318

NW 1028 is a potent VCP/p97 inhibitor. NW 1028 targets the ND1L domain of p97 and inhibits the degradation of a p97-dependent reporter. NW 1028 has good binding affinity with Kd values of 100 and 285 nM for ND1L and full length p97, respectively. NW 1028 has the function of regulating the mitotic spindle of cells.

Product Details

Target	p97
Molecular Weight	415.47
SMILES	O=C(C1=CC(NC(N2)=S)=C(C=C1)C2=O)N3[[email protected]](C(N4[[email protected]](C(N)=O)CCC4)=O)CCC3

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.