Oxaprozin potassium

Cat. No.: IBDI-436760

Oxaprozin potassium is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin potassium also inhibits the activation of NF-κB. Oxaprozin potassium induces cell apoptosis. Oxaprozin potassium shows anti-inflammatory activity. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties.

Product Details

Target	COX | NF-κB | Akt | IKK | Apoptosis
Molecular Weight	331.41
Synonyms	Oxaprozinum potassium, Wy21743 potassium
SMILES	O=C(O[K])CCC1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)O1

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.