P-gp inhibitor 4

Cat. No.: IBDI-433868

P-gp inhibitor 4 (Compound 8b) is a selective P-glycoprotein modulator with an EC50 of 94 nM. P-gp inhibitor 4 increases agent transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells.

Product Details

Target	P-glycoprotein
Molecular Weight	714.85
SMILES	COC1=CC=C(C=C1)S(=O)(N(S(=O)(C2=CC=C(C=C2)OC)=O)C3=CC=C(C=C3)C4=CC=C(C=C4)CN5CCC6=CC(OC)=C(C=C6C5)OC)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.