Cat. No.: IBDA-431811
Size:
Online InquiryTarget Information
| Target Name | p38 (phospho T180 + Y182) |
| Uniprot ID | Q16539 |
| Cellular Localization | Cytoplasm. Nucleus. |
| Immunogen | Synthetic peptide within Human p38 (phospho T180 + Y182). |
| Function | Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. |
Product Details
| Description | PE Rabbit monoclonal antibody to p38 (phospho T180 + Y182). |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A/G purified |
| Isotype | IgG |
| Conjugation | PE |
| Reactivity | Rat |
| Immunogen | Synthetic peptide within Human p38 (phospho T180 + Y182). |
| Positive Control | Flow Cyt: C6 cells treated with staurosporine |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C. Store in the dark |
| Storage Buffer | Preservative: 0.09% Sodium Azide Constituent: 99.71% PBS, 0.2% BSA |