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Palifosfamide tromethamine

Cat. No.: IBDI-437566

Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.

Size (Solid):

Product Details

Target DNA Alkylator/Crosslinker
Molecular Weight 342.16
Synonyms Isophosphoramide mustard tromethamine, IPM tromethamine, ZIO-201 tromethamine
SMILES O=P(NCCCl)(NCCCl)O.NC(CO)(CO)CO

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.