Palmatine hydroxide

Cat. No.: IBDI-431424

Palmatine hydroxide is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine hydroxide can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC50 of 96 μM. Palmatine hydroxide shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities.

Product Details

Target	Indoleamine 2,3-Dioxygenase (IDO) | Virus Protease | Aurora Kinase | Apoptosis | Bacterial | PaRasite
Molecular Weight	369.41
Appearance	Solid
SMILES	COC(C=C1C2=CC3=CC=C4OC)=C(C=C1CC[N+]2=CC3=C4OC)OC.[OH-]
Purity	99.64%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C, 3 years; 4°C, 2 years In solvent: -80°C, 6 months; -20°C, 1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.