Pan Cytokeratin Polyclonal Antibody

Target Information

Target Name	Pan Cytokeratin
Synonyms	pankeratin | pan keratin
Immunogen	Keratin extracted from human skin. Antigen location, cytoplasm. Cross-reactive with keratin from most mammals and birds. In immunohistochemistry nearly all cultured epithelial cell are positive, all non-epithelial cells are negative.

Product Details

Description	Pan Cytokeratin antibody is an unconjugated rabbit polyclonal antibody to human Pan Cytokeratin.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Antiserum
Conjugation	Unconjugated
Modifications	Concentrated
Reactivity	Human
Specificity	The polyclonal antibodies react with keratin of most mammals and birds. A positive reaction is obtained with all stratified squamous epithelia and in epidermal appendages such as hair follicles and sebaceous glands. Also the epithelia of the urinary tract, stomach, small and large intestine, uterine endometrium, bile ducts, prostate, kidney collecting tubules, thymic reticulum cells, mesothelium and to a lesser extent hepatocytes, adenoncarcinomas, transitional cell carcinomas and anaplastic carcinomas can be identified by this antiserum. Renal cell adenocarcinomas and small cell anaplastic lung tumors may remain negative, when examined in paraffin sections. Hepatocytes and pancreatic acini show a positive staining.
Immunogen	Keratin extracted from human skin. Antigen location, cytoplasm. Cross-reactive with keratin from most mammals and birds. In immunohistochemistry nearly all cultured epithelial cell are positive, all non-epithelial cells are negative.
Application	IHC, IHC-Fr, IHC-P

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	Antiserum