PARP1-IN-12

Cat. No.: IBDI-434116

PARP1-IN-12 is a potent PARP1 inhibitor with an IC50 of 2.99 nM. PARP1-IN-12 exhibits antiproliferative activity, can induce cell apoptosis and cause cycle arrest at G2/M phase. PARP1-IN-12 also can induce DNA double strand breaks (DSBs) in BRCA-deficient cells.

Product Details

Target	PARP | Apoptosis
Molecular Weight	741.93
SMILES	FC1=CC=C(CC(C2C=CC=CC23)=NNC3=O)C=C1C(N4CCN(CC4)C(CCCCCCCNCC5C(OC6C5C=C7[[email protected]@](C)(C6)CCC[[email protected]@H]7C)=O)=O)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.