PD-1/PD-L1-IN 6
Cat. No.: IBDI-435388
PD-1/PD-L1-IN 6 (compound A13) is a potent PD-1/PD-L1 interaction inhibitor, with an IC50 of 132.8 nM. PD-1/PD-L1-IN 6 exhibits outstanding immunoregulatory activity. PD-1/PD-L1-IN 6 significantly elevates interferon-γ secretion in a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, without significant toxic effect. PD-1/PD-L1-IN 6 restores the immune response in a T cell-tumor co-culture model.
Product Details
Target |
PD-1/PD-L1 |
Molecular Weight |
402.49 |
SMILES |
O=C(C1=CC=C(CNCCO)C(OC)=C1)N2CCC3=C2C=CC=C3C4=CC=CC=C4 |
Storage & Handling
Shipping |
Room temperature in continental US. May vary elsewhere. |
Storage |
Please store the product under the recommended conditions in the Certificate of Analysis. |
Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.