PD-L1 Monoclonal Antibody

Target Information

Target Name	PD-L1
Uniprot ID	Q9NZQ7
Cellular Localization	Cell membrane and Endomembrane system.
Immunogen	Synthetic peptide.
Function	Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Product Details

Description	Rabbit monoclonal antibody to PD-L1.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide.
Positive Control	WB: Chinese hamster ovary cell lysate stably expressing PD-L1. MDA-MB-231, H1975, NCI-H1299, A549, PC3, DU145, A375, U-87 MG, BXPC-3, NIH:OVCAR-3, SK-OV-3, and HeLa whole cell lysates. Human thymus and placenta tissue lysate. IHC-P: Human placenta, lung carcinoma and tonsil tissues. ICC/IF: CHO-PD-L1 cells. Flow Cyt (Intra): CHO-PD-L1 cells. IP: NCI-H1975 whole cell lysate. IHC-Fr: Frozen human tonsil tissue sections
Application	Flo, ICC/IF, IHC-Fr, IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.