PD-L1 Monoclonal Antibody

Target Information

Target Name	PD-L1
Uniprot ID	Q9NZQ7
Cellular Localization	Cell membrane and Endomembrane system.
Immunogen	Recombinant full length protein corresponding to Human PD-L1 (extracellular).
Function	Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Product Details

Description	Rabbit monoclonal antibody to PD-L1.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant full length protein corresponding to Human PD-L1 (extracellular).
Positive Control	Tissue: Human tonsil, head and neck squamous cell carcinoma and placenta tissues. L2987 cell line. Cell Lines: Positives: B-CPAP (high), ES-2 (medium), HCC70 (low), CHO-PDL1, U-87 MG For additional information - please refer to this publication: Programmed death-ligand 1 (PD-L1) expression in various tumor types - http://www.immunotherapyofcancer.org/content/1/S1/P53 IHC-Fr: Frozen human tonsil tissue sections
Application	Flo, ICC/IF, IHC-Fr, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.