Cat. No.: IBDA-431313
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Online InquiryTarget Information
| Target Name | PD-L1 |
| Uniprot ID | Q9NZQ7 |
| Cellular Localization | Cell membrane and Endomembrane system. |
| Immunogen | Recombinant fragment corresponding to Human PD-L1 aa 1-250. |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. |
Product Details
| Description | Mouse monoclonal antibody to PD-L1. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein G purified |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment corresponding to Human PD-L1 aa 1-250. |
| Positive Control | Recombinant protein fragment of Human PD-L1. Human Hodkin's lymphoma tissue. Programmed death-ligand 1 (PD-L1) expression in various tumor types - http://www.immunotherapyofcancer.org/content/1/S1/P53 |
| Application | Flo, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | Preservative: 0.05% Sodium Azide Constituent: 99% PBS, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |