Cat. No.: IBDA-431313
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Online InquiryTarget Information
Target Name | PD-L1 |
Uniprot ID | Q9NZQ7 |
Cellular Localization | Cell membrane and Endomembrane system. |
Immunogen | Recombinant fragment corresponding to Human PD-L1 aa 1-250. |
Function | Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. |
Product Details
Description | Mouse monoclonal antibody to PD-L1. |
Host Species | Mouse |
Clonality | Monoclonal |
Purity | Protein G purified |
Isotype | IgG2a |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant fragment corresponding to Human PD-L1 aa 1-250. |
Positive Control | Recombinant protein fragment of Human PD-L1. Human Hodkin's lymphoma tissue. Programmed death-ligand 1 (PD-L1) expression in various tumor types - http://www.immunotherapyofcancer.org/content/1/S1/P53 |
Application | Flo, IHC-P, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | Preservative: 0.05% Sodium Azide Constituent: 99% PBS, 0.05% BSA |
Handling | Avoid freeze-thaw cycles. |