Cat. No.: IBDA-431304
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Online InquiryTarget Information
| Target Name | PD-L1 |
| Uniprot ID | Q9NZQ7 |
| Cellular Localization | Cell membrane and Endomembrane system. |
| Immunogen | Synthetic peptide. |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. |
Product Details
| Description | Rabbit monoclonal antibody to PD-L1. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human, Recombinant fragment |
| Immunogen | Synthetic peptide. |
| Positive Control | IHC-P: Human NSCLC tissue. PD L1 transfected HEK-293 cells. Human lung carcinoma and placenta tissue. WB: CHO-PD-L1 (PD-L1 stably expressed Chinese hamster ovary epithelial cell) whole cell lysate. A549 treated with 100ng/ml IFN gamma for 48h whole cell lysate. Human placenta lysate. ICC/IF: CHO-PD-L1 (PD-L1 stably expressed Chinese hamster ovary epithelial cell) cells. IP: ab237726 IP in NCI-H1975 whole cell lysate. mIHC: Human tonsil tissue and Human breast cancer tissue. |
| Application | ELISA, ICC/IF, IHC-P, IP, mIHC, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.05% Sodium Azide Constituent: PBS |
| Handling | Avoid freeze-thaw cycles. |