Cat. No.: IBDA-431302
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Online InquiryTarget Information
Target Name | PD-L1 |
Uniprot ID | Q9NZQ7 |
Cellular Localization | Cell membrane and Endomembrane system. |
Immunogen | Recombinant fragment. |
Function | Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. |
Product Details
Description | Rabbit recombinant multiclonal antibody to PD-L1. |
Host Species | Rabbit |
Clonality | Recombinant Multiclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant fragment. |
Positive Control | WB: NCI-H1975 and MDA-MB-231 whole cell lysates. Human placenta tissue lysate, Human lung carcinoma epithelial cell) cell lysate, CD274 (PD-L1) KO A549, wild-type A549 cell lysate, Wild-type A549, MDA-MB-231 (Human breast adenocarcinoma epithelial cell) cell lysate, NCI-H1975 (Human adenocarcinoma lung epithelial cell) cell lysate IHC-P: Human breast cancer, lung cancer, placenta and tonsil tissue. ICC/IF & Flow Cyt: CHO-PDL1 cells. IP: NCI-H1975 whole cell lysates. |
Application | Flo, I-ELISA, ICC/IF, IHC-P, IP, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 59.94% PBS, 40% Glycerol, 0.05% BSA |
Handling | Avoid freeze-thaw cycles. |