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PF-6683324

Cat. No.: IBDI-435888

PF-6683324 (Trk-IN-4) is a potent pan-Trk inhibitor in cell-based assays with IC50s of 1.9 nM, 2.6 nM and 1.1 nM for TrkA, TrkB and TrkC, respectively. Anti-hyperalgesic effect.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target Trk Receptor
Molecular Weight 521.46
Appearance Solid
Synonyms Trk-IN-4
SMILES O=C(N)C1=C(O[[email protected]]2CCN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)C[[email protected]]2F)N=CC(C4=CN(C)C=N4)=C1
Purity 99.41%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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