Phenoxodiol

Cat. No.: IBDI-438102

Phenoxodiol (Idronoxil), a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP; (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21 WAF1 via a p53 independent manner.

Product Details

Target	Caspase | Apoptosis | TopoisomeRase
Molecular Weight	240.25
Appearance	Solid
Synonyms	Idronoxil, Dehydroequol, Haginin E
SMILES	OC1=CC=C2C=C(C3=CC=C(O)C=C3)COC2=C1
Purity	99.76%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.