Cat. No.: IBDAK-620152
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Online InquiryOverview
| Sample Type | Cell Lysate |
| Detection Method | Colorimetric |
| Assay Type | Semi-quantitative |
| Assay Duration | Multiple steps standard assay |
| Product Type | TLR Signaling |
| Species Reactivity | Reacts with: Mouse |
| Platform | Pre-coated microplate (12 x 8 well strips) |
Target
| Function | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). |
| Sequence Similarities | Belongs to the bZIP family. Jun subfamily. Contains 1 bZIP (basic-leucine zipper) domain. |
| Cellular Localization | Nucleus. |
Storage & Handling
| Storage | Store at +4°C. |
| Storage Buffer | Constituent: 100% PBS |