Cat. No.: IBDA-435483
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Online InquiryTarget Information
| Target Name | PI 3 Kinase p85 Alpha |
| Immunogen | Recombinant fragment within Human PI 3 Kinase p85 alpha (internal sequence). |
| Function | Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. |
Product Details
| Description | Rabbit polyclonal antibody to PI 3 Kinase p85 alpha. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat, Human |
| Immunogen | Recombinant fragment within Human PI 3 Kinase p85 alpha (internal sequence). |
| Positive Control | WB: PC-12, Rat2, Neuro-2a, C8D30, NIH/3T3, Raw 264.7, C2C12, Jurkat, K562 and THP-1 whole cell extracts. IP: Jurkat whole cell extract. IHC-P: Mouse duodenum tissue. |
| Application | IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7 Preservative: 0.01% Thimerosal (Merthiolate) Constituent: 79.99% PBS, 20% Glycerol |
| Handling | Avoid freeze-thaw cycles. |