Cat. No.: IBDA-435325
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Online InquiryTarget Information
| Target Name | PI3-Kinase p170 |
| Uniprot ID | O00443 |
| Cellular Localization | Cell membrane. Golgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle. Nucleus. Cytoplasm. According to PubMed:10766823 and PubMed:11239472, it is found in the cell membrane, the Golgi apparatus and in clathrin-coated vesicles. According to PubMed:17038310 it inserts preferentially into membranes containing PtdIns(4,5)P2. According to PubMed:11606566, it is nuclear and cytoplasmic. Associated with RNA-containing structures. According to PubMed:14563213, it is mainly cytoplasmic. |
| Immunogen | Recombinant fragment. |
| Function | Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2. May play a role in clathrin-coated endocytic vesicle formation and EGF signaling cascade. May be involved in mitosis and UV-induced damage response. May be a downstream effector in insulin signaling cascade. |
Product Details
| Description | Mouse monoclonal antibody to PI 3 Kinase Class 2A/Cpk - BSA and Azide Free. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat |
| Immunogen | Recombinant fragment. |
| Positive Control | WB: Mouse kidney, Mouse testis, Mouse pancreas, Mouse liver, Mouse brain, Rat testis, Rat brain and NIH/3T3, C6 lysates. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.2 Constituent: 100% PBS |
| Handling | Do not freeze. |