PI3K/Akt/mTOR-IN-3

Cat. No.: IBDI-432835

PI3K/Akt/mTOR-IN-3 (compound 3d) is a potent PI3K/AKT/mTOR inhibitor. PI3K/Akt/mTOR-IN-3 displays the inhibitory activity in MCF-7, HeLa and HepG2 cells, with IC50 values of 0.77, 1.23, and 4.57μM, respectively. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 and HeLa cells at the concentration of 4 μM. PI3K/Akt/mTOR-IN-3 induces cell apoptosis and S phase arrest.

Product Details

Target	PI3K | Akt | mTOR | Apoptosis
Molecular Weight	505.77
SMILES	CC1(C)C(C(C[[email protected]]2(C)[[email protected]@]3([H])CC=C4[[email protected]]5([H])CC(C)(C)CC[[email protected]@](C(NCC=C)=O)5CC[[email protected]](C)4[[email protected]@](C)3CC[[email protected]@]12[H])=C)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.