PIM447

Cat. No.: IBDI-435389

PIM447 (LGH447) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis.

Product Details

Target	Pim | Apoptosis
Molecular Weight	440.46
Synonyms	LGH447
SMILES	O=C(C1=CC=C(F)C(C2=C(F)C=CC=C2F)=N1)NC3=C([[email protected]@H]4C[[email protected]](C)C[[email protected]](N)C4)C=CN=C3

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.