Pladienolide B

Cat. No.: IBDI-437484

Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B induces apoptosis.

Product Details

Target	Apoptosis
Molecular Weight	536.70
Appearance	Oil
SMILES	O=C1O[[email protected]](/C(C)=C/C=C/[[email protected]@H](C)C[[email protected]]2O[[email protected]@H]2[[email protected]](C)[[email protected]@H](O)CC)[[email protected]@H](C)/C=C/[[email protected]](OC(C)=O)[[email protected]](C)(O)CC[[email protected]@H](O)C1
Purity	≥96.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Pure form: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.