Products
Inquiry

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Plecanatide

Cat. No.: IBDP-532634

Size:

Target Information

Sequence NDECELCVNVACTGCL (Disulfide bridge: Cys4-Cys12; Cys7-Cys15)
Function Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis.

Product Details

Product Type Peptide
Cas 467426-54-6
Molecular Weight 1681.89 kDa
Purity 0.9814

Storage & Handling

Shipping Shipped at Room Temperature.
Storage Store at -20 °C or -80 °C.
Handling Avoid freeze / thaw cycle.
! For research use only, not intended for any clinical use.