Polygalasaponin F

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Cat. No.: IBDI-431478

Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .

Size (Solid):

Product Details

Target	Toll-like Receptor (TLR) \| PI3K \| Akt \| NF-κB
Molecular Weight	1091.24
Appearance	Solid
SMILES	OC[[email protected]]1O[[email protected]@]([H])(O[[email protected]@H]2[[email protected]@](C)(CO)[[email protected]@](CC[[email protected]]3(C)[[email protected]]4([H])CC=C5[[email protected]@]3(C)CC[[email protected]]6(C(O[[email protected]@H]7O[[email protected]](CO)[[email protected]@H](O)[[email protected]](O)[[email protected]]7O[[email protected]@]8([H])[[email protected]](O)[[email protected]](O)[[email protected]@H](O[[email protected]]9([H])OC[[email protected]@H](O)[[email protected]](O)[[email protected]]9O)[[email protected]](C)O8)=O)[[email protected]@]5([H])CC(C)(C)CC6)([H])[[email protected]]4(C)C[[email protected]@H]2O)[[email protected]](O)[[email protected]@H](O)[[email protected]@H]1O
Purity	99.74%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	4°C *In solvent : -80°C, 6 months; -20°C, 1 month
Handling	Protect from light
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.