Polyinosinic-polycytidylic acid sodium

Cat. No.: IBDI-434723

Polyinosinic-polycytidylic acid (Poly(I:C)) sodium is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis.

Product Details

Target	Toll-like Receptor (TLR) | Apoptosis
Appearance	Solid
Synonyms	Poly(I:C) sodium
SMILES	O[[email protected]]1[[email protected]@H](O[[email protected]](COP(O)(O)=O)[[email protected]]1O)N2C3=C(C(NC=N3)=O)N=C2.O[[email protected]]4[[email protected]](N5C(N=C(N)C=C5)=O)O[[email protected]](COP(O)(O)=O)[[email protected]]4O.[x].[x].[Na].[x]
Purity	≥99.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.