PRMT5-IN-1

Cat. No.: IBDI-434657

PRMT5 IN-1, a hemiaminal, is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 11 nM for PRMT5/MEP50. PRMT5 IN-1 can be converted to aldehydes and react with C449 to form covalent adducts under physiological conditions.

Product Details

Target	Histone MethylTransfeRase
Molecular Weight	418.83
SMILES	O[[email protected]@H]1[[email protected]@H]([[email protected]@H](C2=CC=C(Cl)C=C2)O)O[[email protected]@H](N3C=CC4=C3N=CN5C4=NCC5O)[[email protected]@H]1O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.