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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

PRN694

Cat. No.: IBDI-435342

PRN694 is an irreversible, highly selective and potent covalent interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) dual inhibitor with IC50s of 0.3 nM and 1.4 nM, respectively. PRN694 exhibits extended target residence time on ITK and RLK, enabling durable attenuation of effector cells in vitro and in vivo.

Size (Solid):

Product Details

Target Itk
Molecular Weight 543.67
Appearance Solid
SMILES O=C(C1=CC=C(C(F)F)S1)NC2=NC3=CC(CN[[email protected]@H](C)C(C)(C)C)=CC=C3N2C[[email protected]@H]4N(C(C=C)=O)CCC4
Purity 99.36%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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