PROTAC BRD4 Degrader-15

Cat. No.: IBDI-437192

PROTAC BRD4 Degrader-15 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4, with IC50s of 7.2 nM and 8.1 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-15 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells.

Product Details

Target	PROTACs | Epigenetic Reader Domain
Molecular Weight	1149.29
SMILES	O=C1C2=C3C(C4=CC(CS(C)(=O)=O)=C(C(NCCOC5=CC(CCOCC(N[[email protected]@H](C(C)(C)C)C(N6[[email protected]@H](C[[email protected]](C6)O)C(NCC7=CC=C(C8=C(C)N=CS8)C=C7)=O)=O)=O)=CC(N)=C5)=O)C=C4N(C9=C(C=C(C=N9)F)F)CC3=CN2)=CN1C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.