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PROTAC ER Degrader-4

Cat. No.: IBDI-432575

PROTAC ER Degrader-4 is a von Hippel-Lindau-based PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM.

Size (Solid):

Product Details

Target PROTACs | Estrogen Receptor/ERR
Molecular Weight 1005.19
Appearance Solid
SMILES CC(C)(F)CN1[[email protected]](C2=C(C=C(OCCOCCOCCOCC(N[[email protected]@H](C(C)(C)C)C(N3[[email protected]@H](C[[email protected]@H](O)C3)C(N[[email protected]](C4=CC=C(C5=C(N=CS5)C)C=C4)C)=O)=O)=O)C=C2F)F)C6=C(C7=CC=CC=C7N6)C[[email protected]]1C
Purity 98.22%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.