PROTAC pan-IAP; degrader-1

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Inquiry

Cat. No.: IBDI-433578

PROTAC pan-IAP; degrader-1 (Compound 9) is a pan-IAP; degrader PROTAC. PROTAC pan-IAP; degrader-1 degrades XIAP; , cIAP; 1 and cIAP; 2 with DC50s of 0.7, 2.4, and 6.2 nM in MM.1S cells, respectively.

Size (Solid):

Product Details

Target	PROTACs \| IAP
Molecular Weight	1103.42
SMILES	CN[[email protected]](C(N[[email protected]@H](C1CCCCC1)C(N2C[[email protected]](C[[email protected]]2C(N[[email protected]]3CCCC4=CC=CC=C43)=O)OC5=CC(OCCCCC(N[[email protected]@H](C(C)(C)C)C(N6C[[email protected]@H](C[[email protected]]6C(N[[email protected]](C7=CC=C(C=C7)C8=C(N=CS8)C)C)=O)O)=O)=O)=CC=C5)=O)=O)C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.