PROTAC RAR Degrader-1

Cat. No.: IBDI-436641

PROTAC RAR Degrader-1 comprises a IAP; ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP; 1 are called specific and non-genetic IAP; -dependent protein erasers (SNIPERs).

Product Details

Target	SNIPERs | PROTACs | RAR/RXR
Molecular Weight	917.14
Appearance	Solid
SMILES	O=C(O)C1=CC=C(/C=C/C(C2=CC(C(C)(C)C)=CC(C(C)(C)C)=C2)=O)C=C1OCCCNC(COCCOCCOCCNC([[email protected]](CC(C)C)NC([[email protected]@H](O)[[email protected]](N)CC3=CC=CC=C3)=O)=O)=O
Purity	95.07%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.