Cat. No.: IBDA-433615
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Online InquiryTarget Information
| Target Name | PU.1/Spi1 |
| Uniprot ID | P17947 |
| Cellular Localization | Nucleus. |
| Immunogen | Recombinant full length protein. |
| Function | Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. |
Product Details
| Description | Rabbit monoclonal antibody to PU.1/Spi1 - BSA and Azide Free. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant full length protein. |
| Positive Control | WB: THP-1, U937, Daudi, HeLa whole cell lysates. IHC-P: Human colon and diffuse large B-cell lymphoma FFPE tissue sections. ICC/IF: THP-1 and U-937 cell lines. Flow Cyt (Intra): HeLa and U937 cells IP: THP-1 whole cell lysate. ChIP: U-937 cell line. |
| Application | ChIP, Flo, ICC/IF, IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.20 Constituent: 100% PBS |