PU.1/Spi1 Monoclonal Antibody

Target Information

Target Name	PU.1/Spi1
Uniprot ID	P17947
Cellular Localization	Nucleus.
Immunogen	Recombinant full length protein.
Function	Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.

Product Details

Description	Rabbit monoclonal antibody to PU.1/Spi1.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant full length protein.
Positive Control	WB: THP-1, U937, Daudi, HeLa whole cell lysates. IHC-P: Human colon and diffuse large B-cell lymphoma FFPE tissue sections. ICC/IF: THP-1 and U-937 cell lines. Flow Cyt (Intra): HeLa and U937 cells IP: THP-1 whole cell lysate. ChIP: U-937 cell line.
Application	ChIP, Flo, ICC/IF, IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.