Cat. No.: IBDA-433614
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Online InquiryTarget Information
| Target Name | PU.1/Spi1 |
| Uniprot ID | P17947 |
| Cellular Localization | Nucleus. |
| Immunogen | Synthetic peptide. |
| Function | Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. |
Product Details
| Description | Rabbit monoclonal antibody to PU.1/Spi1 - ChIP Grade. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse |
| Immunogen | Synthetic peptide. |
| Positive Control | WB: RAW264.7, NIH/3T3 and J774A.1 lysates. IHC-P: Mouse spleen and Mouse liver tissues. ICC/IF: RAW 264.7 cells. Flow Cyt (Intra): RAW264.7 cells. IP: J774A.1 cells. |
| Application | ChIP, Flo, ICC/IF, IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |