Cat. No.: IBDA-433616
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Online InquiryTarget Information
Target Name | PU.1/Spi1 |
Uniprot ID | P17947 |
Cellular Localization | Nucleus. |
Immunogen | Synthetic peptide within Human PU.1/Spi1 aa 1-100 (N terminal). |
Function | Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. |
Product Details
Description | Rabbit monoclonal antibody to PU.1/Spi1. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Synthetic peptide within Human PU.1/Spi1 aa 1-100 (N terminal). |
Positive Control | WB: Daudi, THP-1 and Raji Whole cell lysate IHC: human tonsil tissue |
Application | IHC-P, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at -20 °C |
Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 0.05% BSA, 40% Glycerol, 59% PBS |
Handling | Avoid freeze-thaw cycles. |