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PU.1/Spi1 Monoclonal Antibody

Cat. No.: IBDA-433616

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Target Information

Target Name PU.1/Spi1
Uniprot ID P17947
Cellular Localization Nucleus.
Immunogen Synthetic peptide within Human PU.1/Spi1 aa 1-100 (N terminal).
Function Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.

Product Details

Description Rabbit monoclonal antibody to PU.1/Spi1.
Host Species Rabbit
Clonality Monoclonal
Purity Protein A purified
Isotype IgG
Conjugation Unconjugated
Reactivity Human
Immunogen Synthetic peptide within Human PU.1/Spi1 aa 1-100 (N terminal).
Positive Control WB: Daudi, THP-1 and Raji Whole cell lysate
IHC: human tonsil tissue
Application IHC-P, WB

Storage & Handling

Shipping Shipped at 4 °C.
Storage Store at -20 °C
Storage Buffer pH: 7.20
Preservative: 0.01% Sodium Azide
Constituent: 0.05% BSA, 40% Glycerol, 59% PBS
Handling Avoid freeze-thaw cycles.
! For research use only, not intended for any clinical use.