Cat. No.: IBDA-433621
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Online InquiryTarget Information
| Target Name | PU.1/Spi1 |
| Uniprot ID | P17947 |
| Cellular Localization | Nucleus. |
| Immunogen | Recombinant fragment within Human PU.1/Spi1 aa 16-170. |
| Function | Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. |
Product Details
| Description | Mouse monoclonal antibody to PU.1/Spi1. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A/G purified |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment within Human PU.1/Spi1 aa 16-170. |
| Positive Control | IHC-P: Human Hodgkin's lymphoma, colon carcinoma, lymph node and spleen tissues. WB: THP-1 cell lysate. |
| Application | IHC-P, Protein Array, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.05% Sodium Azide Constituent: PBS, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |