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PV-1019

Cat. No.: IBDI-435038

PV-1019 (NSC 744039) is a potent, selective Chk2 inhibitor with an IC50 value of 24 nM. PV-1019 inhibits the Topotecan (HY-13768)-induced Chk2 autophosphorylation. PV-1019 inhibits IR-induced apoptosis.

Size (Solid):

Product Details

Target Checkpoint Kinase (Chk)
Molecular Weight 379.37
Synonyms NSC 744039
SMILES O=C(C(N1)=CC2=C1C([N+]([O-])=O)=CC=C2)NC3=CC=C(/C(C)=N/NC(N)=N)C=C3

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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