Py-MAA-Val-Cit-PAB-MMAE

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Cat. No.: IBDI-434649

Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) is an ADC Linker of Zapadcine-3a. Zapadcine-3a is an anti-TRAILR2 ADC with broad spectrum, and antineoplastic effect. Zapadcine-3a can be swallowed up into lysosome of tumor cells by binding to TRAILR2. Then Zapadcine-3a releases small molecular compound to specifically kill various TRAILR2-pos. Zapadcine-3a potently eradicates tumor cells and cures tumor.

Size (Solid):

Product Details

Target	ADC Linker
Molecular Weight	1446.79
Appearance	Solid
Synonyms	AAJ8D6-PY-Val-Cit-MMAE
SMILES	O[[email protected]@H](C1=CC=CC=C1)[[email protected]@H](C)NC([[email protected]](C)[[email protected]]([[email protected]@]2([H])N(CCC2)C(C[[email protected]@H](OC)[[email protected]]([[email protected]@H](C)CC)N(C)C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CSCCC(N4CN(CN(C4)C(C=C)=O)C(C=C)=O)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
Purity	99.78%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.