QH536

Cat. No.: IBDI-432233

QH536 (Compound 29) is a potent HMGCR degrader with an EC50 of 0.22 μM. QH536 has no side-effect of inducing cholesterol accumulation in cells. QH536 shows anti-inflammatory and can be used for cardiovascular disease and nonalcoholic steatohepatitis research.

Product Details

Target	HMG-CoA Reductase (HMGCR)
Molecular Weight	535.76
SMILES	C[[email protected]@](C1=CC2)(CC(C=NN3C(C)=O)=C3C(C)1C)[[email protected]](CC4)([H])[[email protected]]2([H])[[email protected]@](CC[[email protected]]5([H])[[email protected]](C)CCC(N6CCOCC6)=O)([H])[[email protected]]45C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.