QS-21

Products

Inquiry

Cat. No.: IBDI-431325

QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant. QS-21 stimulates Th2 humoral and Th1 cell-mediated immune responses through action on antigen presenting cells (APCs) and T cells. QS-21 can activate the NLRP3 inflammasome with subsequent release of caspase-1 dependent cytokines, IL-1β and IL-18.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	NOD-like Receptor (NLR)
Molecular Weight	1990.13
Appearance	Solid
Synonyms	Stimulon
SMILES	O=C([[email protected]]1(CCC(C)(C)C2)[[email protected]]2([H])C3=CC[[email protected]@]4([H])[[email protected]@](C)(CC[[email protected]]5([H])[[email protected]@]4(CC[[email protected]](O[[email protected]@](O[[email protected]](C(O)=O)[[email protected]@H](O)[[email protected]@H]6O[[email protected]@](OC[[email protected]@H](O)[[email protected]@H]7O)([H])[[email protected]@H]7O)([H])[[email protected]@H]6O[[email protected]]([[email protected]@H]([[email protected]@H](O)[[email protected]]8O)O)([H])O[[email protected]@H]8CO)[[email protected]@]5(C)C=O)C)[[email protected]]3(C)C[[email protected]]1O)O[[email protected]](O[[email protected]](C)[[email protected]](OC(C[[email protected]@H](O)C[[email protected]]([[email protected]@H](C)CC)([H])OC(C[[email protected]@H](O)C[[email protected]]([[email protected]@H](C)CC)([H])O[[email protected]@H]9O[[email protected]@H](CO)[[email protected]](O)[[email protected]]9O)=O)=O)[[email protected]@H]%10O)[[email protected]@H]%10O[[email protected]@](O[[email protected]@H](C)[[email protected]](O[[email protected]@](OC[[email protected]@H](O)[[email protected]@H]%11O[[email protected]@](OC[[email protected]]%12(O)CO)([H])[[email protected]@H]%12O)([H])[[email protected]@H]%11O)[[email protected]]%13O)([H])[[email protected]@H]%13O
Structure Classification	Terpenoids>Triterpenes
Purity	99.20%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.