(R)-MLT-985

Cat. No.: IBDI-436224

(R)-MLT-985 (compound 11) is a potent MALT1 protease inhibitor with an IC50 of 3 nM. (R)-MLT-985 has an IC50 of 20 nM for MALT1-dependent IL-2 production in Jurkat cells. (R)-MLT-985 suppresses growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells.

Product Details

Target	MALT1
Molecular Weight	448.27
SMILES	O=C(NC1=CC(Cl)=C(N2N=CC=N2)N=C1)NC3=C([[email protected]](OC)C)N4C(N=C3)=CC(Cl)=N4

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.