RALBP1 Monoclonal Antibody

Target Information

Target Name	RALBP1
Uniprot ID	Q15311
Cellular Localization	Membrane.
Immunogen	Synthetic peptide.
Function	Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Product Details

Description	Rabbit monoclonal antibody to RALBP1.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide.
Positive Control	WB: Daudi, MCF7, HT-29, and HeLa cell lysates. IHC-P: Human lung tissue Flow Cyt (Intra): HEK-294T cells.
Application	Flo, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.05% Sodium Azide Constituent: 40% Glycerol, 9.85% Tris Glycine, 50% Tissue Culture Supernatant
Handling	Avoid freeze-thaw cycles.