RALBP1 Polyclonal Antibody

Target Information

Target Name	RALBP1
Uniprot ID	Q15311
Cellular Localization	Membrane.
Immunogen	Recombinant fragment (His-tag) corresponding to Mouse RALBP1 aa 150-400.
Function	Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Product Details

Description	Rabbit polyclonal antibody to RALBP1.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse
Immunogen	Recombinant fragment (His-tag) corresponding to Mouse RALBP1 aa 150-400.
Positive Control	WB: Recombinant mouse RALBP1 and mouse serum. IHC-P: Mouse liver tissue.
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: PBS, 50% Glycerol
Handling	Avoid freeze-thaw cycles.