Rapamycin-13C,d3

Cat. No.: IBDI-434847

Rapamycin- 13C,d3 (Sirolimus- 13C,d3; AY-22989- 13C,d3) is the 13C and deuterium labeled Rapamycin (HY-10219). Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.

Product Details

Target	Isotope-Labeled Compounds
Molecular Weight	918.18
Synonyms	Sirolimus-13C,d3, AY-22989-13C,d3
SMILES	O=C([[email protected]@]1(O)[[email protected]@H](CC[[email protected]@H](C[[email protected]@H](/C(C)=C/C=C/C=C/[[email protected]](C[[email protected]@H](C)C([[email protected]@H]([[email protected]@H](/C(C)=C/[[email protected]]2C)O)OC)=O)C)O[13C]([2H])([2H])[2H])O1)C)C(N3CCCC[[email protected]]3C(O[[email protected]@H](CC2=O)[[email protected]@H](C[[email protected]]4C[[email protected]]([[email protected]](O)CC4)OC)C)=O)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.