Rapamycin-d3

Cat. No.: IBDI-434851

Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.

Product Details

Target	mTOR | FKBP | Autophagy
Molecular Weight	917.19
Appearance	Solid
Synonyms	Sirolimus-d3, AY-22989-d3
SMILES	O=C([[email protected]@]1(O[[email protected]@H](CC[[email protected]]1C)C[[email protected]@H](/C(C)=C/C=C/C=C/[[email protected]](C2)C)OC([2H])([2H])[2H])O)C(N3[[email protected]@H](CCCC3)C(O[[email protected]@H](CC([[email protected]@H](/C=C([[email protected]]([[email protected]](C([[email protected]@H]2C)=O)OC)O)\C)C)=O)[[email protected]@H](C[[email protected]@H]4CC[[email protected]]([[email protected]@H](C4)OC)O)C)=O)=O
Purity	95.48%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.