Recombinant Human EMR1/ADGRE1 (F4/80) Protein

Target Information

Sequence	MRGFNLLLFWGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNT VDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNL SGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVN SMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCN PGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGF APSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF HPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYVSFC AQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSS LATVFLESVESMTLASFWKPSANITPAVRTEYLDIESKVINKECSEENVT LDLVAKGDKMKIGCSTIEESESTETTGVAFVSFVGMESVLNERFFKDHQA PLTTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTLENIQPKQKFERPIC VSWSTDVKGGRWTSFGCVILEASETYTICSCNQMANLAIIMASGELTMGC AIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICA FGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVIN SLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGI FQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKP SSQSQTSRILLSSMPSASKTG
Sequence Similarities	Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. Contains 6 EGF-like domains. Contains 1 GPS domain.
Amino Acids	1 to 821
Cellular Localization	Cell membrane.
Tissue Specificity	Expression is restricted to eosinophils.
Function	Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.

Product Details

Product Type	Protein
Species	Human
Source	Wheat Germ
Protein Length	Full length protein
Molecular Weight	117 kDa
Active	No
Animal free	No
Nature	Recombinant
Application	ELISA, SDS-PAGE, WB

Storage & Handling

Shipping	Shipped with Dry Ice.
Storage	Store at -20 °C or -80 °C.
Handling	Avoid freeze / thaw cycle.