Recombinant Human Neutrophil Bactericidal Protein BP30

Target Information

Sequence	VNPGVVVRISQKGLDYASQQGTAALQKELKRIKIPDYSDSFKIKHLGKGH YSFYSMDIREFQLPSSQISMVPNVGLKFSISNANIKISGKWKAQKRFLKM SGNFDLSIEGMSISADLKLGSNPTSGKPTITCSSCSSHINSVHVHISKSK VGWLIQLFHKKIESALRNKMNSQVCEKVTNSVSSKLQPYFQTLPVMTKID SVAGINYGLVAPPATTAETLDVQMKGEFYSENHHNPPPFAPPVMEFPAAH DRMVYLGLSDYFFNTAGLVYQEAGVLKMTLRDDMIPKESKFRLTTKFFGT FLPEVAKKFPNMKIQIHVSASTPPHLSVQPTGLTFYPAVDVQAFAVLPNS SLASLFLIGMHTTGSMEVSAESNRLVGELKLDRLLLELKHSNIGPFPVEL LQDIMNYIVPILVLPRVNEKLQKGFPLPTPARVQLYNVVLQPHQNFLLFG ADVVYKVDHHHHHH
Sequence Similarities	Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
Amino Acids	32 to 487
Cellular Localization	Secreted. Cytoplasmic granule membrane. Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Tissue Specificity	Restricted to cells of the myeloid series.
Function	The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

Product Details

Product Type	Protein
Species	Human
Source	HEK 293 Cells
Tag	His
Endotoxin Level	<1.0 Eu/µg
Protein Length	Full length protein
Molecular Weight	52 kDa
Purity	>95%
Active	No
Animal free	No
Nature	Recombinant
Application	HPLC, SDS-PAGE

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at -20 °C or -80 °C.
Handling	Avoid freeze / thaw cycle.