Cat. No.: IBDP-531540
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Online InquiryTarget Information
Sequence | MASMTGGQQMGRGHHHHHHENLYFQGGEFARGAEREWEGGWGGAQEEERE REALMLKHLQEALGLPAGRGDENPAGTVEGKEDWEMEEDQGEEEEEEATP TPSSGPSPSPTPEDIVTYILGRLAGLDAGLHQLHVRLHALDTRVVELTQG LRQLRNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKGLRLGHKCFLLSR DFEAQAAAQARCTARGGSLAQPADRQQMEALTRYLRAALAPYNWPVWLGV HDRRAEGLYLFENGQRVSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGT LENCVAQASDDGSWWDHDCQRRLYYVCEFPF |
Sequence Similarities | Contains 1 C-type lectin domain. |
Amino Acids | 22 to 323 |
Cellular Localization | Cytoplasm. Secreted. |
Tissue Specificity | Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver. |
Function | Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation. |
Product Details
Product Type | Protein |
Species | Human |
Source | E. coli |
Protein Length | Full length protein |
Molecular Weight | 37 kDa |
Purity | >90% |
Active | No |
Animal free | No |
Nature | Recombinant |
Application | SDS-PAGE |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at -20 °C or -80 °C. |
Handling | Avoid freeze / thaw cycle. |