Recombinant Human TGFBRAP1 Protein

Target Information

Sequence	RGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSKRLQKEEYHTHLAVL YLEEVLLQRASASGKGAEATETQAKLRRLLQKSDLYRVHFLLERLQGAGL PMESAILHGKLGEHEKALHILVHELQDFAAAEDYCLWCSEGRDPPHRQQL FHTLLAIYLHAGPTAHELAVAAVDLLNRHATEFDAAQVLQMLPDTWSVQL LCPFLMGAMRDSIHARRTMQVALGLARSENLIYTYDKMKLKGSSIQLSDK KLCQICQNPFCEPVFVRYPNGGLVHTHCAASRHTNPSSSSPGTRT
Sequence Similarities	Belongs to the TRAP1 family. Contains 1 CNH domain.
Amino Acids	601 to 860
Cellular Localization	Cytoplasm. Colocalizes with TGF-beta receptors in the absence of signaling.
Function	Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.

Product Details

Product Type	Protein
Species	Human
Source	E. coli
Tag	His
Protein Length	Protein fragment
Molecular Weight	33 kDa
Purity	>80%
Active	No
Animal free	No
Nature	Recombinant
Application	SDS-PAGE

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at -20 °C.
Handling	Avoid freeze / thaw cycle.